Metformin Hydrochloride Extract

1.Molecular Formula: C4H12ClN5
2.Grade Standard: Medicine Grade
3.Usage: Animal Pharmaceuticals
4.Molecular Weight 165.6246
5.Melting point 223-226°C
6.Boiling point 224.1°C at 760 mmHg
7.Flash point 89.3°C
8.Vapour Pressur 0.0929mmHg at 25°C
9.Purity: 99%min
10.Brand Name: REB
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Product Details

Introduction:

Metformin Hydrochloride is a hypoglycemic agent. Metformin hydrochloride extract can reduce the fasting and postprandial hyperglycemia in patients with type 2 diabetes. The HbAlc can decrease by 1% to 2%. The mechanism of reducing blood glucose in 3-(diaminomethylidene)-1 may be:

(1) increasing the sensitivity of the surrounding tissue to insulin and increasing the glucose utilization mediated by insulin.

(2) increase the utilization of glucose by non-insulin-dependent tissues, such as brain, blood cells, renal medulla, intestinal tract, skin and so on.

(3)The inhibition of hepatic gluconeogenesis, decreased glycogen output.

(4)Inhibit the uptake of glucose in the intestinal wall cells.


Specification:

Product Name

Metformin Hydrochloride Extract


CAS

1115-70-4


MF

214-230-6


Type

Antibiotic and Antimicrobial Agents


Grade Standard

Medicine Grade


Usage

Animal Pharmaceuticals


Items

Specifications

Results

Appearance

White to whitish crystal powder

Conforms

Residue on ignition

NMT 0.1%

Conforms

Heavy metal

NMT 20ppm

Conforms

Assay (HPLC)

NLT 99.5%

99.77%

Related substances

NMT 0.5%

0.23%

Single impurity

NMT 0.1%

0.07%

Conclusion:

Complies to the Enterprise standard



Analysis :

Item

Specifications (USP)

Specifications (AJI)

Description

White crystals or crystalline powder

White crystals or crystalline powder

Identification

Infrared absorption spectrum

Infrared absorption spectrum

Specific rotation

[a]D20°

+26.3 °- +27.7°

+26.9 °- +27.9°

Chloride (Cl)

≤ 0.05%

≤ 0.020%

Ammonium (NH4)

---

≤ 0.02%

Sulfate (SO4)

≤ 0.03%

≤ 0.020%

Iron (Fe)

≤ 0.003%

≤ 10PPm

Heavy metals (Pb)

≤ 0.0015%

≤ 10PPm

Loss on drying

≤ 0.5%

≤ 0.5%

Residue on ignition
(sulfated)

≤ 0.3%

≤ 0.10%

Assay

98.5-101.5%

99.0 - 101.0%

Arsenic (As2O3)

--

≤ 1PPm


The Function&Application

1.It is a drug commonleaty used to tr diabetes and cancer.

2.It is used for decreasing blood sugar levels in people with type 2 diabetes.

3.It reduces the amount of sugar made by the liver, limits the amount of sugar absorbed into the body from the diet, and makes insulin receptors more sensitive (helping the body respond better to its own insulin). The effects of metformin hydrochloride extract cause a decrease in blood sugar levels.

4.It is typically taken one to three times a day and comes in several forms and strengths. Metformin HCL comes in tablet form, two different long-acting forms, and a liquid version.


Packing&Delivery

1--Standard Package: 25KG/drum,Double Aseptic food poly bags inside,Paper Drums outside.

1--Sample Package: Aluminum foil bag.

2--Quantity Less than 50kgs, Recommend to take by DHL,UPS,TNT,EMS,Fedex.

3--Quantity Less than 200kgs, Recommend to take Air Shipment.

4--Quantity More than 200kgs, Recommend to take Sea Shipment.

5--Lead Time: By Express Courier, around 4 to 7 days.

By Air, around 2 to 4 days

By Sea, around 7 to 30days.


For More Information, please contact:

information@sxrebecca.com







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