Hesperetin is mainly derived from the young fruit of the genus Citrus, belonging to one of the dihydroflavones, which is pale yellow needle crystal or powder. It is a chemical with a molecular formula of C16H14O6.
As a natural flavonoid compound, hesperidin is widely found in plant, source materials such as fruits, flowers and foods. It has biological and pharmacological activities and is widely used in many fields such as organic chemistry, medicine, agronomy, and food.
Hesperetin can inhibit the action of cholesterol-producing enzymes and esterases, thereby reducing blood fat. Hesperetin can avoid the harm caused by peroxidation by removing peroxynitrite ions. Hesperetin has a stronger anti-inflammatory effect, and hesperetin has an effect on its anti-inflammatory activity after being linked to rutose, and inhibits the inflammatory mediator, thereby indirectly inhibiting the inflammatory response.
Hesperetin has an anti-oxidation effect, which can lead to cancer caused by genetic changes caused by certain factors. Tumors are changes in genes on chromosomes in cells and form abnormally proliferating cell tissues. Experiments have shown that hesperetin can effectively control cancer.
Hesperetin can protect the endothelial cells from hypoxia by stimulating certain mitochondrial enzymes such as succinate dehydrogenase, and prevent thrombosis induced by blood clotting caused by endothelial cell necrosis. The anti-platelet coagulation activity of hesperetin is achieved by inhibiting the phosphorylation of PLCγ2 and its downstream signaling, which can prevent the formation of blood clots and is beneficial to the cardiovascular system.
Hesperetin has important applications in medical research, such as lowering cholesterol, treating diabetic bone disease, and treating acne. Hesperetin has an anti-inflammatory effect, which can reduce the production of sebum, thereby effectively inhibiting the growth of acne. The natural product hesperetin can be used to treat acne.
Hesperetin can also be used in many medical fields such as protecting the cardiovascular, protecting the nerves, and reducing the triglyceride content in the liver.
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