Ginkgo biloba leaf extract is an extract made from the dried leaves of the Ginkgoaceae-Ginkgo biloba with complex chemical components. At present, more than 160 compounds have been isolated from it, including flavonoids, terpenoid lactones, polypentenols, and organic acids. Among them, flavonoids and terpene lactones are the conventional indicators for the quality control of GBE and its preparations, they are also the main active components of GBE, which can improve the microcirculation of the heart and brain vessels, scavenging oxygen free radicals, they are effective in hypertension, arteriosclerosis, and acute brain. It has good curative effect in the treatment of cardiovascular and cerebrovascular diseases such as hypertension, arteriosclerosis and acute cerebral infarction. Ginkgo biloba leaves pill, capsules and dripping pills made from Ginkgo biloba leaf extract are currently very popular edible supplements and medicines in Europe and America.
Flavonoids: mainly include flavonoids and their glycosides, diflavonoids, flavonols and their glycosides, anthocyanins, etc., with a content of 2.5% to 5.91%. Flavonoids have strong antioxidant activity, it can scavenge oxygen free radicals and prevent lipid peroxidation. Among them, quercetin, kaempferol and isorhamnetin can also increase the concentration of Ca2+ in vascular endothelial cells and promote The synthesis and release of NO , thus relaxing blood vessels and improving cardiovascular and cerebrovascular circulation.
Terpenoid lactones: There are 8 in total, divided into diterpenoid ginkgolides and sesquiterpenoid bilobalide according to their structure. Ginkgolides include Ginkgolides A, B, C, J, K, L, and M, which have antiplatelet activating factor activity. Terpenoid lactones are involved in the scavenging process of superoxide anions, which can protect the cell membrane structure, it can be used for the treatment of diseases such as stroke and Alzheimer's. The separation and quality control of Ginkgo biloba terpenoid lactones has become a hot spot in domestic and foreign research. Polypentenols: currently only found in Ginkgo biloba leaves. They are long-chain compounds with 10-20 isopentenyl units linearly connected and terminal isopentenol structure, including cis and trans structures, which are used for medicinal development .
Other active ingredients: Ginkgo biloba leaf extract also contains polysaccharides, phenols, organic acids, amino acids, trace elements, etc.
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