Is pterostilbene and resveratrol the same?

- Nov 21, 2020-

Pterostilbene powder is a dimethylated derivative of resveratrol, which is more effective for certain mechanisms. It is also better absorbed , which is often referred to as "better resveratrol." It looks promising, but the research results are significantly less than its predecessor.

Pterostilbene is a methylated stilbene molecule. It has structural similarity with resveratrol. The only difference is that the two methoxy groups on the pterostilbene molecule replace the hydroxyl groups on the resveratrol molecule. Although most of the effects of the two are equivalent, it seems to be better absorbed after oral intake, it may be a more effective antioxidant and anti-cancer molecule.

Pterostilbene powder





vs

resveratrol

Low-dose pterostilbene (usually 10 mg or less for humans) appears to have certain cognition benefits, it is considered one of the bioactive components of blueberries (along with the anthocyanin content).

Higher doses may not have the neurological effects, but higher doses of pterostilbene powder(usually in the 250-500 mg range) appear to be beneficial in lowering cholesterol and glucose in study animals. The reduction of blood sugar and the improvement of insulin sensitivity are very effective, and some studies have pointed out that it is equivalent to metformin as a reference drug.

The sublingual absorption of red sandalwood has a bioavailability of 25.8+/-13.1%. Pterostilbene powder seems to be better absorbed than resveratrol. Although the absorption is somewhat appreciable (for polyphenols) at lower oral doses, higher oral doses seem to actually be better absorbed than lower doses. it can be absorbed under the tongue.


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