In the field of pesticides, Nonivamide Powder is considered to be an ideal pollution-free pesticide. As early as the 20th century, there were reports about capsaicin as a biological pesticide in the United States and Japan. In 1991, the US Environmental Protection Agency (EPA) recognized capsaicin as a pesticide. After the compounds are biochemical pesticides, the restrictions on their residues on fruits, vegetables and grains are further exempted, and the drug resistance and residue inspections are exempted.
In my country, capsaicin • tea saponin insecticides, capsaicin • nicotine microemulsions, capsaicin • rotenone insecticides, capsaicin microemulsions, abamectin • capsaicin microemulsions and other products have also come out one after another.
The laboratory toxicity test found that Nonivamide has strong toxicity and good control effect on myzus persicae. Studies have shown that capsaicin exhibits strong oviposition avoidance and antifeedant activity against Plutella xylostella. In the field, five insecticides were used to test the efficacy of the diamondback moth and the diamondback aphid. The results showed that the 9% capsaicin nicotine microemulsion had a good control effect on the diamondback moth and the diamondback aphid.
Although the use of capsaicin to control agricultural diseases and insect pests has been reported more, due to the high price of high-purity capsaicin, the application research in the agricultural field is limited to the crude extract of pepper, so it is necessary to do further research to investigate the insecticidal activity of capsaicin. For this reason, capsaicin and its analogue Nonivamide were synthesized by chemical methods through amination reduction and N-acylation (see Figure for the synthesis route).
And measured its indoor insecticidal biological activity, aiming to provide a theoretical basis for further research on the biological activity of capsaicin.
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