How is the application of Scutellaria Baicalensis in medical treatment?

- Jul 20, 2020-

(1) deheating and anti-inflammatory.

Traditional Chinese medicine uses medicine to differentiate the syndromes and treat them. The syndrome of real heat is mostly guided by the treatment of the cold of the heat. Scutellaria Baicalensis is cold, so it has a certain effect on the treatment of the syndrome of real heat in the clinic. In recent years, the anti-inflammatory mechanism and its components have been studied in depth. it can produce anti-inflammatory by interfering with the metabolic pathwayof peanut tetraoleic acid and inhibiting the activity of cytokines.

(2) Remove free radicals and antioxidants:

Free radicals are strongly oxidizing, which can damage the body's cells and tissues, which in turn can lead to chronic diseases and aging. The molecular structure of flavonoids in Scutellaria baicalensis contains phenolic hydroxyl groups, so it has a certain role in scavenging free radicals and anti-oxidation. Baicalein and baicalin are effective antioxidants , and they have a strong scavenging effect on a variety of free radicals, such as superoxide anion, hydroperoxidase, alkane peroxy radicals, and hydroxyl radicals. In addition, baicalein and baicalin can effectively inhibit the metabolism of xanthine oxidase to produce oxygen free radicals, it can be used to treat diseases related to free radicals and oxidative stress.

Scutellaria baicalensis

③Antimicrobial:

Scutellaria baicalensis has a strong antimicrobial effect, and its decoction has a broad-spectrum antibacterial effect. In addition, it can resist various fungi, viruses, mycoplasma, chlamydia and other microorganisms. it and its active ingredients inhibit the growth of bacteria, fungi, and chlamydia, which may be related to its inhibition of the formation of ATP synthase, microbial envelope, and the expression of certain proteins.

④Modern research shows that baicalein has a very good inhibitory effect on microorganisms such as Escherichia coli, Micrococcus fixed, Staphylococcus humane, Staphylococcus epidermidis, fungi such as Candida albicans, etc. Baicalin has shown a certain inhibitory effect on Helicobacter pylori, Staphylococcus aureus, yeast-type fungi, Chlamydia pneumoniae, etc. The latest research found that baicalin can increase the apoptosis rate of yeast-type fungus Candida albicans, the mechanism may be It is related to baicalin inhibiting the activity of succinate dehydrogenase and Ca2+-Mg2+ ATPase, increasing the amount of Ca2+ in the cytoplasm and destroying the ultrastructure of Candida albicans. The combination of baicalein and baicalin with gentamicin, fluconazole, β-lactam antibiotics, etc. will produce a synergistic and enhance the antibacterial.


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