Do you the Magnolia Bark Extract about the Anti-inflammatory and Antioxidant Effect?

- Mar 04, 2020-

Magnolia bark extract is extract from magnolia bark, which uses as a general anti-stress and anti-anxiety agent - so its claims typically center on general benefits in controlling stress and anxiety.  Today let's look at the functions of anti-inflammatory and anti-inflammatory.


Magnolia bark

Anti-inflammatory 

Under the response of inflammatory, cell membrane phospholipids release the arachidonic acid under the action of phospholipase A2. There are two AA metabolic pathways. One is the production of prostaglandins and thromboxins by the action of cyclooxygenase (COX).Another is Lipoxygenase (LO) acts to produce leukotriene (LT). Magnolol at a higher concentration can inhibit the activity of COX in broken cells and at the same time it inhibits the LO metabolic pathway. Therefore, magnolol is a dual inhibitor of COX and LO. The anti-inflammatory effect of magnolol may be related to its inhibition of two metabolic pathways of AA.

Other studies have shown that Magnolia bark extract can exert anti-inflammatory effects by inhibiting TLR4 expression and  activation of downstream NF-κB and MAPKs, thereby it down-regulating the expression of TNF-α, IL-1β and IL-6. In addition, ,Magnolia officinalis P.E can inhibit the release of lysosomal enzymes and reduce the permeability of the capillary wall around the inflammatory site, and which inhibit the migration of white blood cells and fibrous tissue proliferation.

Magnolia Bark Extract

Anti-inflammatory 

Magnolia bark and honokiol have a free radical scavenging effect, which can remove para-hydroxyl radicals and hydrogen peroxide. At the same time, it can protect the activity of mitochondrial respiratory chain enzymes against NADPH-induced peroxidative stress. And it has antagonize the oxidative hemolysis of red blood cells and inhibit lipid peroxidation. A number of in vitro and in vivo studies have examined the antioxidant activity of Magnolia officinalis P.E.

Magnolia Bark Extract Powder

Except the functions what has been discussed, Magnolia officinalis P.E. also has other benefits.

On the one hand, as we all know that if female friends are depressed for a long time and those dissatisfaction are accumulated in the human body.  It is likely to cause further breast hyperplasia. It is very likely that some of them will have the breast cancer. So Magnolia plays an important role in depressing emtion. On the other hand, magnolia bark extract powder can achieve the good stomach-invigorating effect. Under the circumstances that many people do not eat breakfast and three meals are not scheduled or regular. So some people have a bad stomach, so eat more Magnolia is necessary.


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