Can Magnolia Officinalis Extract Loss Weight?

- Mar 24, 2020-

Perceived tension can affect people's eating behavior. Psychological tension is one of the factors that cause overweight and obesity. Magnolia officinalis extract has the effect of anti-anxiety and soothing tension. So it can help weight loss.


Phytochemical studies show that the main components are magnolol, honokiol, and obovatol. The volatile oil extracted from Magnolia officinalis contains β-aminophyllol and a small amount of Magnolitoxin, etc. It can be used clinically for abdominal pain, dysentery, dry stool, cloudy urine, menstrual disorders, weak spleen and stomach, sputum and vomiting, and fullness before the abdomen.

Magnolia officinalis extract

Modern pharmacological studies have shown that Magnolia officinalis has the anti-anxiety, relieves tension, and aids weight loss effects. Much researchers has been done on the role of Magnolia officinalis and preparations containing Magnolia officinalis in anti-anxiety, anti-depression and sedation. Honokiol is an essential ingredient for anxiolytic effects. Magnolia officinalis extract can also activate the benzodiazepine receptor subunit of the GABA-benzodiazepine receptor complex and enhance the chloride ion current, which is consistent with the effect of traditional anxiolytic drugs.


Researchers conducted an anxiety questionnaire on healthy, overweight, premenopausal women and found that a mixture of magnolia and cork was more effective than placebo in reducing temporary and discontinuous anxiety. In a randomized, placebo-controlled, multicenter clinical trial, menopausal women with discomfort symptoms taking a compound capsule that contains the content of Magnolia Extract 60mg and magnesium 50mg for 24 weeks, which can significantly improve sleep disorders and mental disorders. After taking the medicine for 4 weeks, the incidence and severity of symptoms such as flushing, night sweats, palpitations, insomnia, weakness, anxiety, emotional depression, irritability, vaginal dryness, pain during intercourse, and decreased sexual desire were reduced. Ma et al. Reported that honokiol can prolong pentobarbital-induced sleep time, and its role may also be to open the chloride channel of the GABA-benzodiazepine receptor. These show that Magnolia officinalis can be used for anti-anxiety, and its mechanism of action may be related to the activation of GABA receptor-chlorine channels.


Psychological stress is a factor that causes overweight and obesity. Therefore, some people try to reduce the activation of HPA axis by relieving tension. People can use Magnolia officinalis extract relieve tension that may inhibit the increase of cortisol, overweight or obesity caused by tension, especially central obesity. 


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